What is the maximum dosage unit of codeine allowed in Schedule III medications?

In Schedule III medications, the control of codeine is defined under federal and state regulations. Specifically, for a drug to be classified as a Schedule III controlled substance when it contains codeine, it must contain not more than 90 milligrams of codeine per dosage unit. This regulation is designed to balance the potential for misuse of codeine while still allowing the drug to be used therapeutically for pain relief and other medical purposes in appropriate formulations.

The limit of 90 mg ensures that medications remain safe for use and helps to prevent the abuse of higher-potency formulations. Products exceeding this limit are classified differently, typically as Schedule II controlled substances, which come with more stringent regulations due to their higher potential for abuse.

This standard is crucial for pharmacists and healthcare providers to understand, as it guides the prescribing, dispensing, and overall management of medications containing codeine in compliance with the law and to ensure patient safety.